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So the trick comes down to reducing the number of toxins that enter our bodies and eliminating the ones that do. For instance, holes might develop in the retina and there is also a risk of detachment of the retina involved. The dysfunctional immune system produces antibodies that turn against healthy body cells and tissues (antinuclear antibodies). To lose weight, then, you either have to reduce the number of kilojoules you take in, or increase the number of kilojoules you expend on physical activity.