Despite

in spite of; notwithstanding.

contemptuous treatment; insult.

malice, hatred, or spite.

Obsolete . to anger or annoy (someone) out of spite. ?

in despite of

in spite of; notwithstanding

He was tolerant in despite of his background and education.

preposition

against , although , even though , even with , in contempt of , in defiance of , in the face of , notwithstanding , undeterred by , regardless

noun

contempt , contumacy , recalcitrance , recalcitrancy , disdain , scorn , affront , contumely , insult , offense , outrage , slight