to clear, as from an accusation, imputation, suspicion, or the like

to vindicate someone's honor.

to afford justification for; justify

Subsequent events vindicated his policy.

to uphold or justify by argument or evidence

to vindicate a claim.

to assert, maintain, or defend (a right, cause, etc.) against opposition.

to claim for oneself or another.

Roman and Civil Law . to regain possession, under claim of title of property through legal procedure, or to assert one's right to possession.

to get revenge for; avenge.

Obsolete . to deliver from; liberate.

Obsolete . to punish.