loose scales formed on the skin and shed from the coat or feathers of various animals, often causing allergic reactions in susceptible persons.

Informal . anger; temper

Don't get your dander up over such a trifle.

noun

irascibility , irascibleness , spleen , temperament , tetchiness , (slang) anger , anger , dudgeon , ire , provoke , resentment , scurf , temper , wrath