to turn away in feeling or affection; make unfriendly or hostile; alienate the affections of

Their quarrel estranged the two friends.

to remove to or keep at a distance

The necessity for traveling on business has estranged him from his family.

to divert from the original use or possessor.

verb

engage , marry , unite

verb

alien , alienate , antagonize , break up , disaffect , disunify , disunite , divert , divide , divorce , drive apart , leave , make hostile , part , put on the outs , separate , set at odds , sever , split , sunder , turn off * , wean , withdraw , withhold