a sudden, sharp pain

On damp days, he's often bothered by a twinge of rheumatism.

a mental or emotional pang

a twinge of guilt; twinges of sorrow.

to affect (the body or mind) with a sudden, sharp pain or pang.

to pinch; tweak; twitch.

to have or feel a sudden, sharp pain.

noun

ache , bite , gripe , lancination , misery , pang , pinch , prick , shiver , smart , spasm , stab , stitch , throb , throe , tic , tweak , twist , twitch , prickle , soreness , sting , cramp , qualm

verb

ache , pain , pang