a pain located in the head, as over the eyes, at the temples, or at the base of the skull.

an annoying or bothersome person, situation, activity, etc.

noun

annoyance , bane , bother , dilemma , frustration , hassle , hindrance , inconvenience , nuisance , pain in the neck * , pest , predicament , quagmire , trouble , vexation , worry , cephalalgia , megrim , pounding head , splitting headache , throbbing head , millstone , onus , tax , weight , cephalalgy , difficulty , galea , hemicrania , migraine , pain , problem