a condition of general bodily weakness or discomfort, often marking the onset of a disease.

a vague or unfocused feeling of mental uneasiness, lethargy, or discomfort.

noun

good health , healthiness , well being

noun

angst , anxiety , debility , decrepitude , despair , discomfort , disquiet , distress , doldrums , enervation , feebleness , illness , infirmity , infirmness , lassitude , melancholy , pain , sickliness , unease , uneasiness , unhealthiness , weakness , depression , disease , sickness