to reduce or exhaust the strength of, as by exertion; make weary; fatigue

The long walk tired him.

to exhaust the interest, patience, etc., of; make weary; bore

Your stories tire me.

to have the strength reduced or exhausted, as by labor or exertion; become fatigued; be sleepy.

to have one's appreciation, interest, patience, etc., exhausted; become or be weary; become bored (usually fol. by of )

He soon tired of playing billiards.

British Dialect . fatigue.

verb

activate , energize , fire up , invigorate , refresh

verb

annoy , bore , burn out * , bush * , collapse , crawl , debilitate , deject , depress , disgust , dishearten , dispirit , displease , distress , drain , droop , drop , enervate , ennui , exasperate , fag , fail , faint , fatigue , flag , fold , give out , go stale , grow weary , harass , irk , irritate , jade , nauseate , overburden , overstrain , overtax , overwork , pain , pall , peter out * , poop out * , prostrate , put to sleep , sap , sicken , sink , strain , tax , vex , weaken , wear , wear down , wear out , wilt , worry , yawn * , weary , band , exhaust , hoop , lag , recap , retread , rim , shoe , teens , tucker