the act of irritating or the state of being irritated.

something that irritates.

Physiology, Pathology .

the bringing of a bodily part or organ to an abnormally excited or sensitive condition.

the condition itself.

noun

soreness , susceptibility , tenderness , inflammation , excitability , rawness , tenseness , irritability , oversensitiveness , hypersensitivity , oversensitivity , susceptibleness , vexation , exasperation , upset , provocation , anger , annoyance , stress , discomfort , botheration , bothering , harassment , pestering , aggravation , bother , besetment , irritant , nuisance , peeve , plague , torment , chafing , itch , rash , sore