grievous trouble; severe trial or suffering.

an instance of this; an affliction, trouble, etc.

noun

calm , comfort , happiness , peace

noun

adversity , affliction , albatross * , bad luck * , blow * , bummer * , burden , care , cross to bear , crucible * , curse , difficulty , distress , double whammy , downer * , drag * , grief , hard knock , hard time , headache * , heartache * , misery , misfortune , oppression , ordeal , persecution , rainy day , reverse , sorrow , suffering , trial , trouble , vexation , visitation , woe , worry , wretchedness , wronging , cross , crucible , agony , anguish , hardship , pain , unhappiness