the reversing of what has been done; annulling.

a bringing to destruction, ruin, or disaster.

a cause of destruction or ruin.

the act of unfastening or loosing.

Psychiatry . an unconscious defense mechanism through which an attempt is made to reverse a psychologically unacceptable act by doing its opposite, usually repetitiously, in order to relieve anxiety.

noun

building , creation , doing , good fortune

noun

accident , adversity , affliction , bad luck , bad omen , bane , blight , blow , blunder , calamity , casualty , catastrophe , collapse , curse , defeat , destroyer , difficulty , disgrace , doom , downfall , error , failure , fault , faux pas , flaw , fumble , grief , humiliation , last straw * , misadventure , miscalculation , mischance , mishap , misstep , omission , overthrow , overturn , reversal , reverse , ruin , ruination , shame , slip , smash , stumble , subversion , trial , trip , trouble , visitation , weakness , wreck , devastation , havoc , wrack , wreckage , destruction , wrecker , abrogation , annulment , cancellation , defeasance , impoverishment , invalidation , labefaction , misfortune