the isolating, closing off, or surrounding of a place, as a port, harbor, or city, by hostile ships or troops to prevent entrance or exit.

any obstruction of passage or progress

We had difficulty in getting through the blockade of bodyguards.

Pathology . interruption or inhibition of a normal physiological signal, as a nerve impulse or a heart muscle?contraction impulse.

to subject to a blockade.

noun

opening

noun

bar , barricade , blank wall , clog , closure , embolus , encirclement , hindrance , impediment , infarct , infarction , obstacle , obstruction , restriction , roadblock , siege , snag , stop , stoppage , wall , beleaguerment , besiegement , investment , barrier , beleaguer , beset , block , checkpoint , dam , embargo , fence , obstruct

verb

beleaguer , beset , invest , siege