to disturb the mental calm and contentment of; worry; distress; agitate.

to put to inconvenience, exertion, pains, or the like

May I trouble you to shut the door?

to cause bodily pain, discomfort, or disorder to; afflict

to be troubled by arthritis.

to annoy, vex, or bother

Don't trouble her with petty complaints now.

to disturb, agitate, or stir up so as to make turbid, as water or wine

A heavy gale troubled the ocean waters.

to put oneself to inconvenience, extra effort, or the like.

to be distressed or agitated mentally; worry

She always troubled over her son's solitariness.

difficulty, annoyance, or harassment

It would be no trouble at all to advise you.

unfortunate or distressing position, circumstance, or occurrence; misfortune

Financial trouble may threaten security.

civil disorder, disturbance, or conflict

political trouble in the new republic; labor troubles.

a physical disorder, disease, ailment, etc.; ill health

heart trouble; stomach trouble.

mental or emotional disturbance or distress; worry

Trouble and woe were her lot in life.

an instance of this

some secret trouble weighing on his mind; a mother who shares all her children's troubles.

effort, exertion, or pains in doing something; inconvenience endured in accomplishing some action, deed, etc.

The results were worth the trouble it took.

an objectionable feature; problem; drawback

The trouble with your proposal is that it would be too costly to implement.

something or someone that is a cause or source of disturbance, distress, annoyance, etc.

a personal habit or trait that is a disadvantage or a cause of mental distress

His greatest trouble is oversensitivity.

the Troubles,

the violence and civil war in Ireland, 1920?22.

the conflict between Protestants and Catholics in Northern Ireland, beginning in 1969. ?

in trouble

Informal . pregnant out of wedlock (used as a euphemism).

adjective

afflicted , alarmed , asea , bothered , concerned , distraught , distressed , fearful , harassed , irritated , pained , plagued , puzzled , tormented , uneasy , upset , worried