impudence; effrontery.

bile, esp. that of an animal.

something bitter or severe.

bitterness of spirit; rancor. ?

gall and wormwood

bitterness of spirit; deep resentment.

noun

modesty , reservations , shyness

verb

cheer , encourage , enliven , exhilarate , make happy

noun

acrimony , animosity , arrogance , bitterness , brass , brazenness , cheek * , chutzpah * , conceit , confidence , crust cynicism , effrontery , guts * , haughtiness , hostility , impertinence , impudence , insolence , malevolence , malice , overbearance , pomposity , presumption , rancor , sauciness , self-importance , spite , venom , embitterment , rancorousness , resentfulness , virulence , virulency , assumption , audaciousness , audacity , boldness , brashness , cheek , cheekiness , chutzpah , discourtesy , disrespect , face , familiarity , forwardness , impudency , incivility , nerve , nerviness , overconfidence , pertness , presumptuousness , pushiness , rudeness , sassiness , acerbity , anger , assurance , bile , malignity , temerity , wormwood

verb

aggravate , annoy , bedevil , bother , burn , chafe , chide , disturb , exasperate , fret , grate , harass , harry , inflame , irk , nag , peeve , pester , plague , provoke , rile , roil , rub , ruffle , scrape , torment , trouble , vex , worry , abrade , bark , corrode , erode , excoriate , file , fray , frazzle , graze , irritate , scratch , scuff , skin , wear , bug , get , nettle , put out , acerbity , bitterness , boldness , brashness , cheek , effrontery , impudence , nerve , rancor , spite , temerity , vexation