Bướng bỉnh, ngoan cố; khó bảo

(y học) dai dẳng, khó chữa trị

obstinate/stubborn as a mule

như mule

an obstinate disease

bệnh khó chữa trị

adjective

adamant , cantankerous , contradictory , contrary , contumacious , convinced , dead set on , dogged , dogmatic , firm , hard , hardened , headstrong , heady , immovable , indomitable , inflexible , intractable , intransigent , locked in , mulish * , obdurate , opinionated , opinionative , persistent , pertinacious , perverse , pigheaded * , recalcitrant , refractory , relentless , resolved , restive , self-willed , steadfast , strong-minded , tenacious , unalterable , unflinching , unmanageable , unyielding , willful , bullheaded , hardheaded , mulish , pigheaded , stiff-necked , disorderly , fractious , indocile , lawless , obstreperous , uncontrollable , undisciplined , ungovernable , untoward , wild , bulky , crotched , determined , incompliant , muleheaded , pervicacious , staunch , stubborn , sullen , tough , unbending , unpliable , unrepentant , unruly

adjective

agreeable , amenable , cooperative , flexible , helpful , submissive , willing , yielding , compliant , obedient , tractable